Why don’t you just uninstall Windows 10 or create a VM and in both cases directly install the new all-in-one image? https://community.gladysassistant.com/t/gladys-assistant-os-installez-gladys-sur-un-mini-pc-avec-une-simple-cle-usb/
This seems like a much more obvious solution because even with a VM, if you need specific USB ports or folders, etc., it will cause you trouble…