Thanks for your feedback,
Well, here are my first impressions of Gladys after 2 days of use.
I just tested Gladys thanks to your YouTube videos and especially the NodeRed video, so I confirm that your videos are useful for recruiting new users like me 
My equipment:
RFXCOM / Switch / Relay / 433MHz plug
Sonoff equipment (RF, TH, POW, 4CH, DUAL) and other plugs / multi-socket flashed with Tasmota
Magic Home LED strip not flashed
Sony Bravia TV (recovery of status to turn on other equipment)
Freebox Revolution (not yet home automated)
Zigbee CC2531 key flashed for Zigbee2MQTT
4 Aquara Zigbee immersion detection boxes
I have an RFXCOM that doesn’t work natively on Gladys and I have several 433MHz devices that I really need (okay, want is better than need
, home automation is never a need)
Several Sonoff or other plugs flashed with Tasmota and that works pretty well (except for the power strips with the disadvantage explained above)
4 Zigbee boxes in Zigbee2MQTT that work very well in Gladys.
There is also the test if the TV is on or off. I worked on this point. I didn’t find directly in Gladys how to query an API.
Last night I did it via nodered/mqtt and the management in gladys works very well now that you have answered another question to turn on the amp and the subwoofer.
I have a frameless frame controlled via a magic home module that was controlled by domoticz with no problem, for the moment, I haven’t found how to do it in gladys yet but I haven’t looked into it much yet.
I don’t have heating management yet. I’m thinking about it but I haven’t looked into what is compatible with my boiler yet (I want a bus contact and not a dry contact. If you have any leads on this, I’m interested
)
Finally, I have a Bluetooth LED strip that I couldn’t control with domoticz. Once everything is functional, I will look into how to do it with gladys if it’s feasible.
If you want me to test some of my equipment, I can do it to help the project move forward.
Good evening